Research Scientist - The Immunomodulation and Translational Research Program

Job Description

The successful applicant will work with the members of the program to develop new biologics or use the existing ones to modulate the immune system for the prevention of type 1 diabetes and treatment using pancreatic islets or stem cell derived beta cells. Preference will be given to candidates with extensive microsurgical experience with rodent models and molecular and cellular immunology. Experience in deep immunophenotyping, immune cell proliferation assays, and islet transplantation in rodents will be added advantages. The applicant will also contribute to the ongoing research by active participation in lab discussions, grant and manuscript submissions, oral presentations at local, national, and international meetings, and training graduate students and technical personnel for desired techniques as needed. In addition, the successful applicant is expected to contribute significant intellectual input to the progress and direction of the research and take the lead on a project. We are looking for self-motivated individual with strong creative and critical thinking; detail-oriented and goal-driven researcher who is an exceptional team player.

Primary Duties and Responsibilities

• Design and execution of experiments, data collection, analysis, interpretation, and communication of the results.
• Rodent islet isolation, assessment of quality and function in vitro, and transplantation under the kidney capsule, intraportal, or epididymal fat pad.
• Participate in the generation and use of humanized mouse models to assess the efficacy of lead immunomodulatory protocols to prevent rejection of human islets or stem-cell-derived beta cells as prelude to clinical translation.
• Immune monitoring using flow cytometry and immunohistochemistry.
• Perform other duties as assigned.

Qualifications

Minimum Qualifications: Ph.D. or DVM with a minimum of 3 years of postdoctoral experience in immunology with focus on autoimmunity or transplantation. Experience working with mouse models of autoimmunity or transplantation, mammalian tissue culture, immunohistochemistry, flow cytometry, and in vitro/in vivo immune functional assays.

Candidates will be evaluated on: Expertise in multiparameter flow cytometry and basic molecular and cellular immunology techniques. Generation of humanized mice and their use for transplantation, handling mice and performing various manipulations, including injections via different routes, harvesting lymphoid tissues and blood for deep immunophenotyping.

Anticipated Hiring Range

$55,000-$70,000 annually

Application Materials

Be prepared to upload a CV.

Benefit Eligibility

This position is eligible for University benefits. The University offers a comprehensive benefits package, including medical, dental and vision plans, retirement, and educational fee discounts. For additional information on University benefits, please visit the Faculty & Staff Benefits website at http://www.umsystem.edu/totalrewards/benefits

Values Commitment

We value the uniqueness of every individual and strive to ensure each person’s success. Contributions from individuals with diverse backgrounds, experiences and perspectives promote intellectual pluralism and enable us to achieve the excellence that we seek in learning, research and engagement. This commitment makes our university a better place to work, learn and innovate.

In your application materials, please discuss your experiences and expertise that support these values and enrich our missions of teaching, research and engagement.

Equal Employment Opportunity

Equal Opportunity is and shall be provided for all employees and applicants for employment on the basis of their demonstrated ability and competence without unlawful discrimination on the basis of their race, color, national origin, ancestry, religion, sex, pregnancy, sexual orientation, gender identity, gender expression, age, disability, protected veteran status, or any other status protected by applicable state or federal law. This policy shall not be interpreted in such a manner as to violate the legal rights of religious organizations or the recruiting rights of military organizations associated with the Armed Forces or the Department of Homeland Security of the United States of America. For more information, call the Director of Employee and Labor Relations at 573-882-7976.

To request ADA accommodations, please call the Director of Accessibility and ADA at 573-884-7278.

Know Your Rights

To read more about Equal Employment Opportunity (EEO) please use the following links:

• Know Your Rights English Version
• Know Your Rights Spanish Version

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