Sr Laboratory Specialist

Sr Laboratory Specialist

Job Summary

The Clement lab uses cutting-edge genomic technologies to understand the bio-molecular mechanisms of disease. Specifically, we are pioneering the use of single-cell technologies and CRISPR genome editing to understand how DNA mutations give rise to cancer using human cell line models. We are looking for enthusiastic, curious, self-motivated individuals with a strong work ethic who will be responsible for planning, organizing, and carrying out experiments to achieve these goals with other members of the Clement lab and as part of collaborations with other researchers at the University of Utah. Successful candidates will assist the Principal Investigator by supporting efficient laboratory operations and assisting with general lab duties. As the Clement lab also has a strong computational focus, there may be opportunities for further computational training. The applicant will join a team of scientists and trainees with a variety of backgrounds and skill sets as part of a vibrant and engaging community 

Responsibilities
Essential Functions
1. Maintains and passages human cell lines under sterile conditions.
2. Prepares RNA and DNA libraries following detailed protocols.
3. Plans, organizes, and conducts experiments.
4. Applies independent judgment to assess the validity of data collected and to interpret results.
5. Devises, refines, optimizes, and implements new techniques or modifies existing processes by utilizing advanced knowledge.
6. Prepares, operates, and maintains laboratory and experimental testing equipment.
7. Purchases laboratory supplies and materials.
8. Collaborates with the Principal Investigator and the setting up of new methods and assays to accomplish scientific objectives, preparation of Environmental Health and Safety (EHS) / Office of Environmental Health and Safety (OEHS) protocols, and preparation of reports, manuscripts, and grants.
9. May coauthor research papers and publications.
10. May represent the University by presenting research and findings to peers at conventions and conferences.



Minimum Qualifications
Bachelor’s degree in an appropriate scientific discipline or equivalency (one year of education can be substituted for two years of related work experience), plus four years of related full-time laboratory experience required. Demonstrated human relations and effective communication skills also required.

Applicants must demonstrate the potential ability to perform the essential functions of the job as outlined in the position description.

Preferences
Preferences:
• Advanced Education: Master’s degree in Molecular Biology, Genetics, Biochemistry, or a related field.
Experience:
o Extensive experience with single-cell DNA library preparation and sequencing.
o Experience with automated liquid handling systems and high-throughput workflows.
o Previous work with CRISPR genome editing and understanding of its applications in single-cell analysis.
o Significant experience in human cell culture, including handling various human cell lines and performing cell-based assays.
o Familiarity with University of Utah IACUC and EHS / OEHS protocols
Skills:
o Strong data analysis skills, including familiarity with bioinformatics tools and software.
o Ability to troubleshoot and optimize experimental protocols.
o Excellent organizational skills and attention to detail.
o Strong communication and teamwork skills, with the ability to work collaboratively in a multidisciplinary environment.
o Lab and project management.
o Mentoring and training junior lab members and students.
o Strong background in molecular biology techniques, including PCR, DNA extraction, and quantification.
o Proficiency in handling and processing small volumes of biological samples.
o Experience with next-generation sequencing (NGS) library preparation, preferably single-cell DNA libraries.
o Familiarity with single-cell technologies and platforms, such as Mission Bio, 10x Genomics, or similar.
o Demonstrated ability to follow detailed protocols and maintain accurate records of experiments and results.
o Proficiency in human cell culture techniques, including maintaining and passaging cell lines under sterile conditions.



Special Instructions


Requisition Number: PRN38923B
Full Time or Part Time? Full Time
Work Schedule Summary: Monday through Friday, 9:00am - 5:00pm. This position is not eligible for telecommuting. 
Department: 00241 - Biomedical Informatics
Location: Campus
Pay Rate Range: $39,300 - $68,349
Close Date:
Open Until Filled: Yes

To apply, visit https://utah.peopleadmin.com/postings/166358


jeid-b31f7cac57067546893bf7bb505caf46