Research Associate

Research Associate


Location: Philadelphia, PA
Open Date: Mar 29, 2023
Deadline: Apr 27, 2023 at 11:59 PM Eastern Time

The labs of Drs. Andres Blanco and Christopher Lengner in the Department of Biomedical Sciences in the School of Veterinary Medicine at the University of Pennsylvania seek candidates for a Research Associate position in the Academic Support Staff. This appointment will be initially for one (1) year and continuation during that time period and renewal are based on satisfactory performance and availability of funding (limited to three (3) years). This position is focused on the investigation of the molecular regulation of cellular programs driving colorectal cancer (CRC) oncogenesis and metastasis. Expertise is required in the areas of mouse models of CRC, mouse and human organoid models of CRC, and genetic manipulation of CRC cells. The most competitive candidates will also have experience using forward genetic screening and competence with orthotopic CRC transplantation methodology such as endoscope-guided implantation.


Qualifications
Applicants must have a Ph.D. degree and a strong publication record in CRC or related fields. Responsibilities may include: cell culture of CRC organoids and cell lines, lentiviral manipulation of organoids and cell lines, molecular cloning, deployment of CRISPR screens, some proficiency bioinformatics analysis of next-generation sequencing data from RNA-seq and CRISPR sgRNA libraries, mouse breeding and genotyping, mouse colony maintenance, CRC orthotopic implantations, and mouse dissections and histological analyses.


Application Instructions
Applications should be submitted here in Interfolio. A resume and three references are required, using those who would be able to submit a recommendation letter on their behalf.


To apply, visit https://apply.interfolio.com/122775

The University of Pennsylvania values diversity and seeks talented students, faculty and staff from diverse backgrounds. The University of Pennsylvania is an equal opportunity and affirmative action employer. Candidates are considered for employment without regard to race, color, sex, sexual orientation, gender identity, religion, creed, national or ethnic origin, citizenship status, age, disability, veteran status or any other legally protected class. Questions or concerns about this should be directed to the Executive Director of the Office of Affirmative Action and Equal Opportunity Programs, University of Pennsylvania, 421 Franklin Building, 3451 Walnut Street, Philadelphia, PA 19104-6205; or (215) 898-6993 (Voice) or (215) 898-7803 (TDD).
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