Research Scientist Protein Biochemist
- Employer
- Dartmouth College
- Location
- New Hampshire, United States
- Salary
- Salary Not Specified
- Date posted
- Oct 28, 2022
View more
- Position Type
- Faculty Positions, Science, Technology & Mathematics, Other Science & Technology, Administrative, Academic Affairs, Research Administration
- Employment Type
- Full Time
Job Details
Position Details
Position Information
Posting date
10/27/2022
Closing date
Open Until Filled
Yes
Position Number
1128292
Position Title
Research Scientist Protein Biochemist
Department this Position Reports to
Dartmouth Institute of Biomolecular Targeting
Hiring Range Minimum
Please inquire
Hiring Range Maximum
Please inquire
SEIU Level
Not an SEIU Position
FLSA Status
Exempt
Employment Category
Regular Full Time
Scheduled Months per Year
12
Scheduled Hours per Week
40
Schedule
Location of Position
Hanover, NH
Remsen Level 3,
Remote Work Eligibility?
Onsite only
Is this a term position?
No
If yes, length of term in months.
N/A
Is this a grant funded position?
Yes
Position Purpose
The Dartmouth Institute for Biomolecular Targeting (bioMT) is seeking an experienced staff member to join its Core Facilities (Molecular Tools Core and Molecular Interactions and Imaging Core). The successful applicant will possess knowledge and hands-on experience on the design, production, and biophysical characterization of recombinant proteins. The Protein Biochemist will employ high-throughput approaches for construct design and protein expression and develop purification workflows involving multiple chromatographic methods (e.g., AP, IEC, SEC ). Previous experience with structural analysis (x-ray, or cryoEM) of proteins and/or in proteomics will be highly desirable. This person will actively contribute to and facilitate multidisciplinary research projects across the Dartmouth community. Other activities include but are not limited to, data collection and reporting, equipment maintenance, and training of bioMT investigators.
Description
Required Qualifications - Education and Yrs Exp
PhD or equivalent combination of education and experience
Required Qualifications - Skills, Knowledge and Abilities
- High competency in basic laboratory skills (pipetting, weighing, sterile technique, and recordkeeping), molecular cloning, and one or more of bacterial, insect, or mammalian cell culture.
- Experience with protein purification methods and equipment.
- Ability to learn, develop, and apply new techniques.
- Ability to work independently and apply critical thinking and sound judgment.
- Good organizational and time management skills.
- Ability to multitask.
- Ability to draft clear technical protocols.
- Willingness to work with hazardous materials including biological agents and/or hazardous chemicals.
- Knowledge of computers and software applications.
- Excellent communication skills.
- Willingness to work closely with diverse groups of students and research staff, including the ability to manage and resolve conflicts.
Four+ years of relevant research experience or the equivalent work in a laboratory is highly desirable
Department Contact for Cover Letter and Title
Andreia Verissimo
Equal Opportunity Employer
Dartmouth College is an equal opportunity/affirmative action employer with a strong commitment to diversity and inclusion. We prohibit discrimination on the basis of race, color, religion, sex, age, national origin, sexual orientation, gender identity or expression, disability, veteran status, marital status, or any other legally protected status. Applications by members of all underrepresented groups are encouraged.
Background Check
Employment in this position is contingent upon consent to and successful completion of a pre-employment background check, which may include a criminal background check, reference checks, verification of work history, and verification of any required academic credentials, licenses, and/or certifications, with results acceptable to Dartmouth College. A criminal conviction will not automatically disqualify an applicant from employment. Background check information will be used in a confidential, non-discriminatory manner consistent with state and federal law.
Special Instructions to Applicants
This position is funded by a grant. Continuation is based upon available funds.
All Dartmouth College employees, whether working on-site or remotely, are required to be up to date with vaccination against COVID -19 (or to have received an approved exemption from vaccination through the Office of Institutional Diversity and Equity). Please visit https://dartgo.org/vaxpolicy for details. Compliance with this requirement is a condition of employment. Failure to meet this condition of employment within the first 30 days may result in Dartmouth in its sole discretion ending employment.
Dartmouth College has a Tobacco-Free Policy. Smoking and the use of tobacco-based products (including smokeless tobacco) are prohibited in all facilities, grounds, vehicles or other areas owned, operated or occupied by Dartmouth College with no exceptions. For details, please see our policy. https://policies.dartmouth.edu/policy/tobacco-free-policy
Additional Instructions
Quick Link
https://searchjobs.dartmouth.edu/postings/65540
Key Accountabilities
Description
Research/Experiments
- Works collaboratively with core facility staff, faculty, scientists, and graduate students from across the Dartmouth community to express and purify recombinant proteins for use in research projects.
- Independently designs optimal constructs for protein production in E. coli, HEK293, and Sf9/Hi5 cells.
- Independently optimizes expression conditions and develops purification protocols for diverse protein targets.
- Develops proficiency in laboratory equipment for protein expression, purification, and characterization, including AKTA systems, centrifuges, and a variety of analytical instruments.
- Gains experience with diverse biochemical and biophysical techniques, including SPR, ITC, Fluorescence polarization and X-ray Crystallography.
- Supports proteomics projects by helping with sample preparation, LC-MS/MS applications, and data analysis.
- Prepare and optimize protein samples for structure determination by cryoEM to support structural biology research projects.
- As needed, supports eukaryotic cell culture services, including culture maintenance and transfection.
- Troubleshoots and recommends solutions to problems associated with experimental design, procedures, and equipment.
65
Description
Data Collection/Preparation
- Collects, analyzes, and interprets data resulting from expression and purification experiments.
- Performs literature searches to develop information of relevance to current projects.
- Prepares appropriate and understandable representations of data such as sequence files, graphs, charts, etc.
- Participates in the preparation of annual reports.
- Presents data at laboratory meetings, departmental retreats, and scientific conferences.
- Contributes to the preparation of scientific manuscripts by drafting portions of the text, preparing graphs, tables, and charts, etc. as needed.
15%
Description
Laboratory
- Adheres to laboratory safety requirements including general, biological, and chemical/hazardous waste safety disposal methods.
- Develops SOPs and other documentation for common procedures and methods.
- Develops and tracks quality-assurance and quality-control metrics.
- Maintains hardcopy and computerized records associated with laboratory activities.
10%
Description
Training
- Provides training in laboratory methods, procedures, and techniques to multiple levels of scientific investigators (graduate students, post-doctoral fellows, staff scientists and faculty).
- Develops instructional materials as needed.
10%
-
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Demonstrates a commitment to diversity, inclusion, and cultural awareness through actions, interactions, and communications with others.
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Performs other duties as assigned.
Supplemental Questions
Required fields are indicated with an asterisk (*).
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here
(Open Ended Question)
Required Documents
- Cover Letter
- Curriculum Vitae
- Additional Document #1
Company
Employment at Dartmouth
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