Postdoctoral Research Associate - Barth/Zhao Lab
- Employer
- Carnegie Mellon University
- Location
- Pittsburgh, Pennsylvania, United States
- Salary
- Competitive Salary
- Date posted
- Aug 30, 2022
View more categoriesView less categories
- Position Type
- Faculty Positions, Health Sciences, Other Health & Medicine, Science & Mathematics, Biology & Life Sciences, Other Science & Technology
- Employment Type
- Full Time
Job Details
The laboratories of Dr. Alison Barth and Dr. Yongxin Zhao seek a joint position for a Postdoctoral Associate with interest and experience in development of novel techniques on nanoscale protein imaging in the mammalian central nervous system. We are looking for a person who is excited about science and wants to move the needle!
The position will involve development and validation of a newly developed expansion microscopy approach for nanoscale imaging of proteins in mouse brain systems with ~20 nm resolution. The major goal is to apply this imaging method to validate putative thalamocortical synaptic contacts modified during learning and detected from volumetric confocal imaging and 2P imaging. Synapses will be detected and validated by imaging and analyzing the same objects before and after enhanced expansion microscopy. This project will build upon the collaborations between Barth lab and Zhao lab and will extend the Expansion Pathology methods developed by Dr. Zhao.
Strong applicants will have some expertise in fluorescent imaging, neurobiology, and computational image analysis. A Ph.D. degree in a STEM field is required. The position will be fully supported by a grant administrated by NIH. The salary is competitive and commensurate with experience.
Qualifications
– Ph.D. in any of STEM fields
Minimum skills – highlight all that apply
– At least 4 years of Biology/Chemistry research lab experience, especially in the field of neuroscience or biological imaging.
– Ability to independently work on multiple projects.
– Hand-on experiences in neurosurgery on mouse, installing skull optical clearing window
– Hands on experience in fluorescence microscopy, in vivo 2P imaging preferred.
– Must possess a high level of initiative and the ability to work with minimal supervision.
– Excellent writing, communication and interpersonal skills.
– Motivation to learn and develop new techniques and desires to apply them to address tractable scientific questions.
Minimum physical mobility – highlight all that apply
-Ability to stoop, reach, bend at waist, grasp
-Ability to lift and carry equipment up to 25 pounds
Preferred qualifications, education and experience
– Expertise in Neuroscience research.
– Expertise in immunohistochemistry and immunofluorescence.
– Computer programming experience (Matlab, Python or R preferred).
– Data analysis experience.
Exposure – none
Job functions –
– Development of novel imaging technologies to detect and validate synaptic contacts found in 2P in vivo imaging.
– New member training
– Other duties as assigned.
Application Instructions
Applications, including a cover letter, curriculum vitae indicating your interest and contact information for three reference should be submitted electronically via Interfolio.
Equal Employment Opportunity Statement
Carnegie Mellon University shall abide by the requirements of 41 CFR §§ 60-1.4(a), 60-300.5(a) and 60-741.5(a). These regulations prohibit discrimination against qualified individuals based on their status as protected veterans or individuals with disabilities, and prohibit discrimination against all individuals based on their race, color, religion, sex, or national origin. Moreover, these regulations require that covered prime contractors and subcontractors take affirmative action to employ and advance in employment individuals without regard to race, color, religion, sex, national origin, protected veteran status or disability.
Company
Carnegie Mellon University challenges the curious and passionate to imagine and deliver work that matters.
A private, global research university, Carnegie Mellon stands among the world's most renowned educational institutions, and sets its own course.
Carnegie Mellon was founded in 1900 by Andrew Carnegie under the premise that a school established to foster and develop the technical skills of its students would soon produce students and graduates whose work would astound Pittsburgh and the world. Over 120 years later, our institution continues to produce talented alumni and draws faculty and staff eager to be a part of the university's creative, passionate and close-knit community. We place emphasis on practical problem solving, interdisciplinary learning, an entrepreneurial spirit, and collaboration.
Over the past 10 years, more than 400 startups linked to CMU have raised more than $7 billion in follow-on funding. Those investment numbers are especially high because of the sheer size of Pittsburgh’s growing autonomous vehicles cluster – including Uber, Aurora, Waymo and Motional – all of which are here because of their strong ties to CMU.
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Robotics and software engineering lead the way. The city is home to Google, Uber and Apple offices and a budding ecosystem of tech startups including Duolingo, Modcloth and 4Moms, all of which have CMU roots.
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