The Department of Medicine – Section of Immunology, Allergy &
Rheumatology is seeking a full-time dedicated scientist to
undertake research projects in the field of DNA damage repair,
innate and adaptive immune responses, and allergic inflammation.
The research will focus on the identification of the roles of DNA
repair proteins in protein-interactomes that regulate chronic
airway lung and brain inflammation. Human tissue samples, tissues
from complex animal models involving wild-type and gene-knockout
mice and/or cultured cells will be utilized and analyzed using the
most advanced molecular technologies and advanced single-cell
techniques such as DNA damage and repair analysis, bulk and
scRNAseq, proximity ligation assay, mass spectrometry, CYTOF,
Nanostring, protein and DNA interactomes, innate and adaptive
immune responses and many other assays. The postdoctoral associate
will work under the general guidance of the principal investigator
(Dr. Sanjiv Sur's laboratory;
collaboratively with other scientists in the same and other
partnering laboratories. A recent Ph.D. degree that requires
exposure to Immunology is highly desirable but not essential. The
candidate must possess a proactive, team-oriented attitude with a
strong work ethic and excellent multi-task and organizational
Scientific experiments and duties
- Plans, directs, and conducts specialized and advanced research
- Designs and accurately performs in vivo and in vitro
experiments involving animals and humans.
- Collects and correctly processes cells from human and mice
tissues and cultured cells for single-cell preparations, DNA damage
and repair analysis, bulk and scRNAseq, proximity ligation assay,
mass spectrometry, CYTOF, Nanostring, protein and DNA interactomes,
innate and adaptive immune responses.
- Modifies and constantly improves the planned experiments based
on self-critique and input from colleagues and PI.
- Coordinates activities with other scientists in the PI’s lab
and with other collaborating labs.
- Effectively uses and arranges core labs for
immunohistochemistry, flow cytometry, DNA and RNA sequencing, mass
- Writes original manuscripts with the data generated, and
reviews articles. Carefully reviews literature to write paper and
- Contributes to writing parts of grants.
- Presents data in daily lab meetings, local meetings and
- Orders lab items and animals.
- Checks all functionality and safety of equipment in the lab
- Manages cryotanks and refrigerators.
- Manages and contributes to safety in the lab.
- Writes and revises animal and human protocols.
- MD or Ph.D. in Basic Science, Health Science, or a related
- No experience.
- A recent Ph.D., MD or MD-PhD degree with exposure to Immunology
and/or DNA damage repair is highly desirable but not
- Having prior original first-author publications in high-impact
journals is highly desirable.
- Possessing a proactive, team-oriented attitude with a strong
work ethic and having excellent multi-tasking and organizational
skills is highly desirable.
- Previous experience in coordinating complex research activities
and presenting data in national meetings is preferred.
Baylor College of Medicine is an Equal Opportunity/Affirmative
Action/Equal Access Employer.
CA; CH; PD