Postdoctoral Fellow in Parasitic Diseases: Drug Discovery and Therapeutics
- Employer
- Loyola University Chicago
- Location
- Illinois, United States
- Salary
- Salary Not Specified
- Date posted
- Jul 24, 2019
View more
You need to sign in or create an account to save a job.
Position Details
Position Details
Job Title
Postdoctoral Fellow in Parasitic Diseases: Drug Discovery and Therapeutics
Position Title
Postdoctoral Fellow in Parasitic Diseases: Drug Discovery and Therapeutics
Position Number
Job Category
University Faculty
Job Type
Full-Time
FLSA Status
Exempt
Campus
Maywood-Health Sciences Campus
Location Code
DEPARTMENT OF MEDICINE (06500A)
Department Name
Is this split and/or fully grant funded?
Duties and Responsibilities
Searching for a post-doctoral research fellow in the Department of Medicine, Loyola University Medical Center, Chicago, USA . Our primary focus is to develop high throughput screening methods for identifying lead compounds using new drug libraries, synthetic molecules, approved drugs and natural products for treating protozoan diseases, specifically Malaria, Leishmaniasis, Chagas disease and Toxoplasmosis. These parasites are still continuing to be threat globally, currently no vaccines and treatment primarily depended on pharmacotherapy. Rapid emergence of drug resistance to commonly used drugs, coupled with limited availability of second-line therapeutics creates an immediate need to discover new and effective drugs. Besides the problem of drug resistance and toxicity, currently used drugs cause adverse effects on the host immune system (immune dysregulation). Therefore, our approach is to discover and develop drugs that target parasite as well have beneficial effect on the host immune response. Furthermore, we will utilize in-silico analysis, including molecular docking and structure-based screening to identify putative targets, mechanisms of actions of each lead compounds and in-vitro enzymatic assays to validate. Our lab is also interested in understanding the molecular and biological mechanisms underlying anemia caused by inflammation using an in-vitro erythropoiesis model.
Qualifications
We seek highly motivated researcher with previous experience of working with at least one of the parasite, drug discovery and/or therapeutic development areas. Required skills include tissue culture, parasite culture, in-vitro screening in parasites, flow cytometry, RT- PCR, microscopy imaging, functional enzymatic assays and related molecular biology techniques. Applicants should have excellent writing skills and able to work both independently and collaboratively. Applicants should have a Ph.D. (or expected to receive a Ph.D.) in the biomedical sciences or M.D. equivalent at the time of joining the lab.
Physical Demands
Working Conditions
Minimum Education and/or Work Experience
Searching for a post-doctoral research fellow in the Department of Medicine, Loyola University Medical Center, Chicago, USA . Our primary focus is to develop high throughput screening methods for identifying lead compounds using new drug libraries, synthetic molecules, approved drugs and natural products for treating protozoan diseases, specifically Malaria, Leishmaniasis, Chagas disease and Toxoplasmosis. These parasites are still continuing to be threat globally, currently no vaccines and treatment primarily depended on pharmacotherapy. Rapid emergence of drug resistance to commonly used drugs, coupled with limited availability of second-line therapeutics creates an immediate need to discover new and effective drugs. Besides the problem of drug resistance and toxicity, currently used drugs cause adverse effects on the host immune system (immune dysregulation). Therefore, our approach is to discover and develop drugs that target parasite as well have beneficial effect on the host immune response. Furthermore, we will utilize in-silico analysis, including molecular docking and structure-based screening to identify putative targets, mechanisms of actions of each lead compounds and in-vitro enzymatic assays to validate. Our lab is also interested in understanding the molecular and biological mechanisms underlying anemia caused by inflammation using an in-vitro erythropoiesis model.
We seek highly motivated researcher with previous experience of working with at least one of the parasite, drug discovery and/or therapeutic development areas. Required skills include tissue culture, parasite culture, in-vitro screening in parasites, flow cytometry, RT- PCR, microscopy imaging, functional enzymatic assays and related molecular biology techniques. Applicants should have excellent writing skills and able to work both independently and collaboratively. Applicants should have a Ph.D. (or expected to receive a Ph.D.) in the biomedical sciences or M.D. equivalent at the time of joining the lab.
Interested applicants should submit a cover letter, CV and contact information of three references to: pkempaiah@luc.edu
Open Date
12/14/2018
Close Date
Special Instructions to Applicants
Interested applicants should submit a cover letter, CV and contact information of three references to: pkempaiah@luc.edu
Diversity and Inclusion Statement
Quick Link for Posting
https://www.careers.luc.edu/postings/9915
Job Number
Organizational Location
HEALTH SCIENCES CAMPUS
Posting Details
Posting Detail
Number of Vacancies
1
Desired Start Date
Position End Date
Open Until Filled
Yes
Applicant Documents
Required Documents
- Curriculum Vitae
- Cover Letter/Letter of Application
- Teaching Statement
- Research Statement
- Writing Sample
- Scholarly Publications
- Teaching Evaluations
- Other Document
- Unofficial Transcripts
- Multi Media
- Resume
Required fields are indicated with an asterisk (*).
You need to sign in or create an account to save a job.
Get job alerts
Create a job alert and receive personalized job recommendations straight to your inbox.
Create alert