Professional Research Assistant
We are encouraging applications for a Professional Research Assistant with Dr. Charles Hoeffer's Lab.
The University of Colorado Boulder is committed to building a culturally diverse community of faculty, staff, and students dedicated to contributing to an inclusive campus environment. We are an Equal Opportunity employer, including veterans and individuals with disabilities.
Who We Are
The Institute for Behavioral Genetics (IBG) is an organized research unit of the University of Colorado Graduate School dedicated to conducting and facilitating research on the genetic and environmental bases of individual differences in behavior. Within IBG, the Hoeffer lab uses mouse models to study the neurological underpinnings of genetically derived neurological diseases and disorders. Our studies range from assays of animal behavior to molecular analyses of neuromolecular signaling. To accomplish this, our lab employs a comprehensive battery of technical approaches. Our behavioral work utilizes well-validated mouse behavioral paradigms modeling human behavior with automated video capture-based behavioral assessments. We combine these assays with other techniques to manipulate the brain using viral transfection, brain region-specific genetic and pharmacological interventions, and in vivo electrophysiological recording. We have expertise in several areas of cognition: memory formation, spatial learning, affective behaviors, extinction learning, circadian activity, and social behavior. Our lab also uses ex vivo brain slice electrophysiology to examine neuronal circuit function and signaling in the hippocampus and other brain regions. We also use primary neuronal culture to ask more detailed neurophysiological questions at the single neuron level. The biochemical studies conducted in the lab include western analyses, spectrophotometric enzymatic assays, and real-time quantitative PCR to study molecular signaling pathways involved in neuronal function. We hope that this multi-faceted approach allows us to more deeply explore the mechanistic nature of human neuropsychiatric disorders and neurodegenerative diseases and then translate our findings to improved diagnostics and therapies for human patients. The lab has two significant areas of focus, with several smaller sub-projects contained within them. This position will start as a ½ time position but may increase to full-time as our projects develop.
What Your Key Responsibilities Will Be
Your specific responsibilities in this position will be to assist the lab in animal colony maintenance associated with studies of neurological disorders and diseases using the transgenic animal models and, following training, electrophysiological recording from ex vivo brain slice preparations.
What We Can Offer
Starting salary is $33,280 /year.
The University of Colorado offers excellent benefits , including medical, dental, retirement, paid time off, tuition benefit and ECO Pass. The University of Colorado Boulder is one of the largest employers in Boulder County and offers an inspiring higher education environment. Learn more about the University of Colorado Boulder .
Be Adaptable. Be Encouraged. Be Boulder.
What We Require
- BA / BS, Molecular Biology or Neuroscience preferred.
What You Will Need
- Experience with mouse husbandry and colony management.
- Experience with molecular biological techniques related to DNA isolation and PCR and gel running.
What We Would Like You To Have
- Completed IACUC training and have experience with CU Boulder OAR procedures and facilities.
- Experience with protein lysate preparation and western blot assays.
- Mouse behavioral experience with assays related fear extinction, affective behaviors, and spatial memory.
- Experience with cardiac perfusions for tissue fixation and cryostat sectioning.
To apply, please submit the following materials:
- Cover Letter
- 1 Letter of Recommendation (Not Confidential)
Review of applications will begin immediately and will continue until the position is filled.
Note: Application materials will not be accepted via email. For consideration, applications must be submitted through CU Boulder Jobs.
Posting Contact Information
Posting Contact Name: Charles Hoeffer
Posting Contact Email: Charles.Hoeffer@colorado.edu
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