One of the primary goals of the laboratory, which is part of the Center for Cell and Gene Therapy, at Baylor College of Medicine, is to develop and test novel immunotherapies to treat viral infections and cancer, and my laboratory is currently conducting clinical trials of novel T cell therapies developed to target a spectrum of diseases ranging from COVID-19 to leukemia, lymphoma and pancreatic cancer.
About the Center for Cell & Gene Therapy
The Center for Cell and Gene Therapy interacts with basic research and clinical departments at Baylor College of Medicine and affiliated hospitals to discover and develop novel therapies for a range of diseases including cancer, HIV and cardiovascular diseases. It is our intention to have the capability of moving basic pre-clinical discoveries into the clinical phase of development for initial evaluation in our patients. These combined genetic and cellular therapies should enable us to treat a range of conditions, both congenital and acquired, in almost every system of the body. For more information, please visit our website at https://www.bcm.edu/academic-centers/cell-and-gene-therapy .
Under the supervision of the Principal Investigator, the Research Associate will design, direct, and conduct experiments requiring high level expertise in the laboratory environment, particularly in handling primary human immune cells such as T cells. The Research Associate will also conduct laboratory experiments on research projects with an immunotherapy focus that fall within well-defined guidelines; keep abreast of current publications relative to methods, techniques, and developments within area of research; collects, prepares, and analyzes specimens including primary human immune cells (or animal subjects); evaluates results of (or response to) process; summarizes data; may provide supervision and guidance to junior level technicians.
- Collect, prepare, analyze, dissect, and evaluate specimens such as primary human immune cells including T cells and/or in vitro cell cultures.
- Perform calculations to complete research test results; collates data; performs statistical analysis of lab results and maintain notes and log or computer database; performs basic procedures for computer assisted data analysis.
- Track patient progress through a series of functional immune studies including IFNg ELISpot analysis, Luminex Multiplex Assay, DNA isolation for TCR sequencing.
- Perform data management, organizing and analysis of assay results.
- Coordinate with the research coordinator to schedule patient blood collections, processing samples, perform correlative studies, bank reference materials and compile reports for frequent updates.
- Create research summaries in multiple formats, including spreadsheets, PowerPoint presentations, graphs and standard, written summaries.
- Assists in maintaining required records on equipment and procedures and assists in maintaining/cleaning/calibrating equipment used for cell processing.
- Master's degree in Basic Science or a related field. Experience in lieu of degree will not be accepted.
- Three years of relevant experience typically as a Research Assistant, Research Technician or Postdoctoral Fellow/Associate.
- PhD with 3 years of relevant experience.
Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.
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