Research Assistant Professor - Cerebrovascular Research (67278)



A Research Assistant Professor position is available to study the neuroinflammatory mechanisms of blood-brain barrier damage in ischemic stroke in the laboratory of Dr. Eduardo Candelario-Jalil (Department of Neuroscience, McKnight Brain Institute, University of Florida). The laboratory is focused on understanding the role of inflammatory mediators in blood-brain barrier breakdown in rodent models of focal cerebral ischemia. Studies will utilize multiple approaches including magnetic resonance imaging (MRI), immunoblotting, immunohistochemistry, and fluorescence resonance energy transfer (FRET)-based biochemical assays to measure the activity of specific matrix metalloproteinases. Job duties include: 1) performing surgeries in rodents to induce ischemic stroke; 2) conducting behavioral tests; 3) performing molecular and histological studies including immunoblotting, matrix metalloproteinase activity assays, ELISA, RNA isolation and quantitative PCR, and brain microvessel isolation; 4) perform flow cytometry to study immune cell infiltration into the ischemic brain; 5) performing in vitro cell culture experiments using brain endothelial cells and microglial cultures; and 6) genotyping of transgenic mouse strains. Other job duties also include data analysis, preparation of figures, and drafting manuscripts for submission to specialized journals and grant applications, working with the IACUC to maintain compliance with animal protocols. Moreover, the applicant will play a key role in training students (undergraduate and graduate) and postdoctoral fellows in laboratory-specific methodologies and experimental protocols.

Minimum Requirements

  • Candidates must hold a Ph.D. and have a strong background in neuroscience, pharmacology, and molecular and cell biology.
  • At least three years of postdoctoral training in the cerebrovascular research field is required.
  • The candidate is expected to have high level of independence in conducting in vivo and in vitro experiments, collecting the data, as well as preparing manuscripts for publication and grant submissions.
  • Proficiency in written and spoken English is required.


Preferred Qualifications

  • High level of experience with rodent models of focal cerebral ischemia (intraluminal middle cerebral artery occlusion and permanent ligation of the middle cerebral artery) is highly desirable.
  • Extensive biological research laboratory experience including cell culture, immunofluorescence, immunoblotting, qPCR, and flow cytometric analysis.
  • Genotyping and experience in maintaining transgenic mouse colonies.
  • Experience with Microsoft Office (Word, Excel, PowerPoint), Photoshop and GraphPad Prism (statistical program) preferred.


For consideration, please attach a curriculum vitae (CV) and letter of interest with your application. We will begin reviewing applications December 7, 2020 with interviews continuing until the position is filled.

The University of Florida is committed to non-discrimination with respect to race, creed, color, religion, age, disability, sex, sexual orientation, gender identity and expression, marital status, national origin, political opinions or affiliations, genetic information and veteran status in all aspects of employment including recruitment, hiring, promotions, transfers, discipline, terminations, wage and salary administration, benefits, and training.

If an accommodation due to a disability is needed to apply for this position, please call 352-392-2477 or the Florida Relay System at 800-955-8771 (TDD). Hiring is contingent upon eligibility to work in the US. Searches are conducted in accordance with Florida's Sunshine Law.

Selected candidate will be required to provide an official transcript to the hiring department upon hire. A transcript will not be considered "official" if a designation of "Issued to Student" is visible. Degrees earned from an education institution outside of the United States are required to be evaluated by a professional credentialing service provider approval by National Association of Credential Evaluation Services (NACES), which can be found at http://naces.org/ .

The University of Florida is committed to non-discrimination with respect to race, creed, color, religion, age, disability, sex, sexual orientation, gender identity and expression, marital status, national origin, political opinions or affiliations, genetic information and veteran status in all aspects of employment including recruitment, hiring, promotions, transfers, discipline, terminations, wage and salary administration, benefits, and training.

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