Research Technician III
The Garcia laboratory in BCM's Center for Drug Discovery has NIH support to identify novel male contraceptive targets through high throughput transcriptomics and proteomics approaches, to understand the functional significance of these novel targets through genetically manipulated mouse models, and to develop small-molecule inhibitors against identified functionally relevant targets.
The end goal of the work is to define the functional requirement of novel male contraceptive targets, to mechanistically define the molecular functions of key spermatogenic or epididymal proteins, and to accelerate successful drug discovery research.
•Prepares and conducts laboratory research experiments.
•Collects, compiles and analyzes data
•Conducts literature searches and summarizes information in an appropriate format for a particular study.
•Documents results of experiments.
•Selects, evaluates and applies techniques used in routine research.
•Orders laboratory supplies and equipment.
•Mouse husbandry, including breeding, weaning, and genotyping animals; male reproductive tissue dissection, processing for histology and immunohistochemistry; mouse epididymal sperm isolation for computer assisted sperm analysis; human and mouse DNA and RNA isolation for PCR and high-throughput sequencing techniques; management of human and animal protocols; placing lab orders; and troubleshooting problems as they occur.
•Performs other job related duties as assigned.
- Education Required: Bachelor's degree in a Basic Science or related field. Four years of related experience may substitute for degree requirement.
- Experience Required: One year of relevant experience.
- Certification/Licenses/Registration: None Required.
- Education Preferred: Master's degree in a related field.
- Bachelor’s degree in Biology or a related discipline.
- Hands-on laboratory experience in genetics, reproductive biology, biochemistry, medicinal/organic chemistry, and/or a related field.
- Experience with one or more of the following: DNA and/or RNA isolation, PCR, mouse husbandry, tissue dissection, and histology and/or immunohistochemistry.
- Excellent interpersonal skills and an ability to work in a team environment.
Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.
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